The Indian payroll compliance stack, for a US reader
US payroll has a familiar shape: withholding, a quarterly return, a year-end form. India has the same shape and different parts, and the parts do not map one-to-one.
TDS is tax deducted at source on salaries — the withholding equivalent. It is deposited monthly and reported quarterly on Form 24Q, and at year end each employee receives a Form 16, which is the closest analogue to a W-2. The EPF ECR is the monthly Provident Fund filing; Provident Fund is India's mandatory retirement contribution, roughly comparable in function to a 401(k) but statutory rather than elective. ESI is Employees' State Insurance, a contributory medical and cash-benefit scheme that applies to employees earning up to ₹21,000 a month in gross pay. Professional Tax is a small state-level levy, typically around ₹200 a month, with its own schedule in each state.
Each of those has its own deadline, its own portal and its own consequence for being late. Running them is less about difficulty than about never missing one, twelve times a year, in every state where you employ someone.